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  1. Ductal carcinoma in-situ (DCIS) is a pre-invasive form of invasive breast cancer (IBC). Due to improved breast cancer screening, it now accounts for ~ 25% of all breast cancers. While the treatment success rat...

    Authors: Marija Debeljak, Soonweng Cho, Bradley M. Downs, Michael Considine, Brittany Avin-McKelvey, Yongchun Wang, Phillip N. Perez, William E. Grizzle, Katherine A. Hoadley, Charles F. Lynch, Brenda Y. Hernandez, Paul J. van Diest, Wendy Cozen, Ann S. Hamilton, Debra Hawes, Edward Gabrielson…
    Citation: Breast Cancer Research 2024 26:178
  2. Breast cancer subtypes Luminal A and Luminal B are classified by the expression of PAM50 genes and may benefit from different treatment strategies. Machine learning models based on H&E images may contain featu...

    Authors: Dong Neuck Lee, Yao Li, Linnea T. Olsson, Alina M. Hamilton, Benjamin C. Calhoun, Katherine A. Hoadley, J. S. Marron and Melissa A. Troester
    Citation: Breast Cancer Research 2024 26:177
  3. Disparities in breast cancer mortality persist despite improvements in screening and therapeutic options. Understanding the impact of social determinants of health on disparate breast cancer outcomes is challe...

    Authors: Kayla A. Councell, Ann M. Polcari, Rachel Nordgren, Ted A. Skolarus, Andrew J. Benjamin and Sarah P. Shubeck
    Citation: Breast Cancer Research 2024 26:176
  4. Triple negative breast cancer (TNBC) is the most aggressive subtype of breast cancer. While PD-1 based immunotherapies overall have led to improved treatment outcomes for this disease, a diverse response to fr...

    Authors: Payton De La Cruz, Julia McAdams, Melanie Morales Aquino, Aileen I. Fernandez, Andrew Elliott, Maryam Lustberg, Christoph Schorl, Jennifer R. Ribeiro and Nicole E. James
    Citation: Breast Cancer Research 2024 26:175
  5. Breast cancer is one of the most common cancers in women and is closely associated with obesity. Gremlin-2 (GREM2), an antagonist for bone morphogenetic proteins (BMPs), has been considered an inhibitor of adi...

    Authors: Jiwoo Jung, Na Hui Kim, Jayeon Park, Dayeon Lim, Minji Kwon, World Gil, Suyeon Jung, Minjeong Go, Chaeeon Kim, Ye Hwang Cheong, Mee-Hyun Lee, Hee Sun Park, Yong-Bin Eom and Sin-Aye Park
    Citation: Breast Cancer Research 2024 26:174
  6. Breast cancer, which is the most prevalent form of cancer among women globally, encompasses various subtypes that demand distinct treatment approaches. The tumor microenvironment and immune response are of cru...

    Authors: Jingyang Liu, Wen Sun, Ning Li, Haibin Li, Lijuan Wu, Huan Yi, Jianguang Ji and Deqiang Zheng
    Citation: Breast Cancer Research 2024 26:172
  7. To assess proportions of metastatic recurrence in women initially diagnosed with non-metastatic breast cancer by stage at diagnosis, breast cancer subtype, calendar period and age.

    Authors: Eileen Morgan, Colette O’Neill, Richa Shah, Oliver Langselius, Yaqi Su, Clara Frick, Hanna Fink, Aude Bardot, Paul M. Walsh, Ryan R. Woods, Lou Gonsalves, Jan F. NygÃ¥rd, Serban Negoita, Esmeralda Ramirez-Pena, Karen Gelmon, Nicoleta Antone…
    Citation: Breast Cancer Research 2024 26:171
  8. Breast cancer (BCa) is a major global health challenge. The BCa genome often carries extensive somatic copy number alterations (CNAs), including gains/amplifications and losses/deletions. These CNAs significan...

    Authors: Parastoo Shahrouzi, Youness Azimzade, Wioletta Brankiewicz-Kopcinska, Sugandha Bhatia, David Kunke, Derek Richard, Xavier Tekpli, Vessela N. Kristensen and Pascal H. G. Duijf
    Citation: Breast Cancer Research 2024 26:170
  9. Prolactin, a hormone produced by the pituitary gland, regulates breast development and may contribute to breast cancer etiology. However, most epidemiologic studies of prolactin and breast cancer have been res...

    Authors: Jacob K. Kresovich, Catherine Guranich, Serena Houghton, Jing Qian, Micheal E. Jones, Maegan E. Boutot, Mitch Dowsett, A. Heather Eliassen, Montserrat Garcia-Closas, Peter Kraft, Aaron Norman, Michael Pollak, Sabina Rinaldi, Bernard Rosner, Minouk J. Schoemaker, Christopher Scott…
    Citation: Breast Cancer Research 2024 26:169
  10. Up to 40% of patients with estrogen receptor (ER)-positive breast cancer will develop resistance against the majority of current ER-directed therapies. Resistance can arise through various mechanisms such as i...

    Authors: Jane Foo, Francesco Gentile, Shabnam Massah, Helene Morin, Kriti Singh, Joseph Lee, Jason Smith, Fuqiang Ban, Eric LeBlanc, Robert Young, Natalie Strynadka, Nada Lallous and Artem Cherkasov
    Citation: Breast Cancer Research 2024 26:168
  11. Patients with Triple Negative Breast Cancer (TNBC) currently lack targeted therapies, and consequently face higher mortality rates when compared to patients with other breast cancer subtypes. The tumor microen...

    Authors: Noah M. Chernosky, Ilaria Tamagno, Kelsey L. Polak, E. Ricky Chan, Xueer Yuan and Mark W. Jackson
    Citation: Breast Cancer Research 2024 26:167
  12. Elevated mammographic density is associated with increased breast cancer risk. However, the contribution of longitudinal changes in mammographic density to breast cancer risk beyond initial mammographic densit...

    Authors: Parisa Tehranifar, Erica J. Lee Argov, Shweta Athilat, Yuyan Liao, Ying Wei, Alexandra J. White, Katie M. O’Brien, Dale P. Sandler and Mary Beth Terry
    Citation: Breast Cancer Research 2024 26:166
  13. Presently incurable, metastatic breast cancer is estimated to occur in as many as 30% of those diagnosed with early-stage breast cancer. Timely and accurate identification of those at risk for developing metas...

    Authors: Gina M. Gehling, Miad Alfaqih, Lisiane Pruinelli, Angela Starkweather and Jennifer R. Dungan
    Citation: Breast Cancer Research 2024 26:165
  14. Authors: Yoonwon Kook, Young-jin Lee, Chihhao Chu, Ji Soo Jang, Seung Ho Baek, Soong June Bae, Yoon Jin Cha, Gyungyup Gong, Joon Jeong, Sae Byul Lee and Sung Gwe Ahn
    Citation: Breast Cancer Research 2024 26:164

    The original article was published in Breast Cancer Research 2024 26:154

  15. Tissue stiffness, dictated by organisation of interstitial fibrillar collagens, increases breast cancer risk and contributes to cancer progression. Tamoxifen is a standard treatment for receptor-positive breas...

    Authors: Sara Göransson, Pablo Hernández-Varas, Mattias Hammarström, Roxanna Hellgren, Magnus Bäcklund, Kristina Lång, Ann H. Rosendahl, Mikael Eriksson, Signe Borgquist, Staffan Strömblad, Kamila Czene, Per Hall and Marike Gabrielson
    Citation: Breast Cancer Research 2024 26:163
  16. The clinical management of breast cancer (BC) is mainly based on the assessment of receptor expression by tumour cells. However, there is still an unmet need for novel biomarkers important for prognosis and th...

    Authors: Meron Yohannes, Zelalem Desalegn, Marcus Bauer, Kathrin Stückrath, Endale Anberbir, Yonas Bekuretsion, Mathewos Assefa, Tariku Wakuma, Yasin Worku, Pablo S. C. Santos, Lesley Taylor, Adamu Adissie, Claudia Wickenhauser, Chiara Massa, Martina Vetter, Eva Johanna Kantelhardt…
    Citation: Breast Cancer Research 2024 26:162
  17. The clinically high comorbidity between polycystic ovary syndrome (PCOS) and breast cancer (BC) has been extensively reported. However, limited knowledge exists regarding their shared genetic basis and underly...

    Authors: Kaixin Bi, Miaoran Chen, Qianru Zhao, Tongtong Yang, Wenjia Xie, Wenqi Ma and Hongyan Jia
    Citation: Breast Cancer Research 2024 26:161
  18. Human epidermal growth factor receptor 2-targeted (HER2) therapy with antibody-drug conjugates has proven effective for patients with HER2-low breast cancer. However, intratumoral heterogeneity (ITH) poses a g...

    Authors: Haoquan Chen, Yulu Liu, Jiaqi Zhao, Xiaoxuan Jia, Fan Chai, Yuan Peng, Nan Hong, Shu Wang and Yi Wang
    Citation: Breast Cancer Research 2024 26:160

    The Correction to this article has been published in Breast Cancer Research 2024 26:173

  19. Growing epidemiological evidence suggests an association between exposure to air pollutants and breast cancer. Yet, the underlying mechanisms remain poorly understood. This study explored the mediating role of...

    Authors: Benoît Mercoeur, Béatrice Fervers, Thomas Coudon, Hwayoung Noh, Camille Giampiccolo, Lény Grassot, Elodie Faure, Florian Couvidat, Gianluca Severi, Francesca Romana Mancini, Pascal Roy, Delphine Praud and Amina Amadou
    Citation: Breast Cancer Research 2024 26:159
  20. It has been suggested that the association between body mass index and breast cancer risk differs between Asian women and Western women. We aimed to assess the associations between body mass index and breast c...

    Authors: Keiko Wada, Koshi Kuboyama, Sarah Krull Abe, Md. Shafiur Rahman, Md. Rashedul Islam, Eiko Saito, Chisato Nagata, Norie Sawada, Akiko Tamakoshi, Xiao-Ou Shu, Ritsu Sakata, Atsushi Hozawa, Seiki Kanemura, Hidemi Ito, Yumi Sugawara, Sue K. Park…
    Citation: Breast Cancer Research 2024 26:158
  21. Several studies have confirmed the potential value of applying radiomics to predict prognosis of breast cancer. However, the tumor segmentation in these studies depended on delineation or annotation of breast ...

    Authors: Lang Xiong, Xiaofeng Tang, Xinhua Jiang, Haolin Chen, Binyan Qian, Biyun Chen, Xiaofeng Lin, Jianhua Zhou and Li Li
    Citation: Breast Cancer Research 2024 26:157
  22. Fibroepithelial lesions (FELs) of the breast encompass a broad spectrum of lesions, ranging from commonly encountered fibroadenomas (FAs) to rare phyllodes tumors (PTs). Accurately diagnosing and grading these...

    Authors: Conrad Lee, Heilum Yip, Joshua J.X. Li, Joanna Ng, Julia Y. Tsang, Thomson Loong and Gary M. Tse
    Citation: Breast Cancer Research 2024 26:156
  23. Cancer metastasis remains a major challenge in the clinical management of triple-negative breast cancer (TNBC). The NF-κB signaling pathway has been implicated as a crucial factor in the development of metasta...

    Authors: Xiaoxiao Zuo, Xiaohan Zhao, Xiaofei Zhang, Qingyuan Li, Xingyu Jiang, Shumei Huang, Xuwei Chen, Xiangfu Chen, Weihua Jia, Hequn Zou, Dongni Shi and Xueke Qian
    Citation: Breast Cancer Research 2024 26:155
  24. HER2-positivity is an essential marker for therapeutic decisions, while HER2 expression is heterogenous. In recent years, there has been increasing recognition of a subgroup of breast cancer patients who have ...

    Authors: Yoonwon Kook, Young-jin Lee, Chihhao Chu, Ji Soo Jang, Seung Ho Baek, Soong June Bae, Yoon Jin Cha, Gyungyup Gong, Joon Jeong, Sae Byul Lee and Sung Gwe Ahn
    Citation: Breast Cancer Research 2024 26:154

    The Correction to this article has been published in Breast Cancer Research 2024 26:164

  25. Breast cancer, one of the most common forms of cancer, is associated with the highest cancer-related mortality among women worldwide. In comparison to other types of breast cancer, patients diagnosed with the ...

    Authors: Jasmine M. Manouchehri, Jharna Datta, Lynn M. Marcho, Jesse J. Reardon, Daniel Stover, Robert Wesolowski, Uma Borate, Ting-Yuan David Cheng, Patrick M. Schnell, Bhuvaneswari Ramaswamy, Gina M. Sizemore, Mark P. Rubinstein and Mathew A. Cherian
    Citation: Breast Cancer Research 2024 26:153
  26. Chemo-endocrine therapy can lead to various side effects associated with ovarian dysfunction. Predicting menstrual recovery is necessary to discuss the treatment-related issues regarding fertility and prematur...

    Authors: Young Joo Lee, Woo Chul Noh, Sungchan Gwark, Hyun-Ah Kim, Jai Min Ryu, Seung Il Kim, Eun-Gyeong Lee, Seock-Ah Im, Yongsik Jung, Min Ho Park, Kyong Hwa Park, Su Hwan Kang, Joon Jeong, Eunhwa Park, Sung Yong Kim, Min Hyuk Lee…
    Citation: Breast Cancer Research 2024 26:152
  27. Menopausal hormone therapy (MHT) is associated with an increased risk of postmenopausal breast cancer, predominantly the luminal A-like subtype. The impact of MHT on deaths from breast cancer subtypes is less ...

    Authors: Marit Busund, Giske Ursin, Eiliv Lund, Sairah Lai Fa Chen and Charlotta Rylander
    Citation: Breast Cancer Research 2024 26:151
  28. Gestational diabetes mellitus (GDM) is a common pregnancy complication characterized by insulin resistance. A link has been suggested between insulin resistance and breast cancer, which is the most common canc...

    Authors: Maria Hornstrup Christensen, Christina Anne Vinter, Thomas Bastholm Olesen, Maria Houborg Petersen, Ellen Aagaard Nohr, Katrine Hass Rubin, Marianne Skovsager Andersen and Dorte Moeller Jensen
    Citation: Breast Cancer Research 2024 26:150
  29. Invasive lobular breast cancer (ILC) is the most common special type of breast cancer and has unique clinicopathological and molecular hallmarks that differentiate it from the more common invasive carcinoma—no...

    Authors: Susrutha Puthanmadhom Narayanan, Abdalla M. Wedn, Osama Shiraz Shah, Jian Chen, Daniel D. Brown, Priscilla F. McAuliffe, Steffi Oesterreich and Adrian V. Lee
    Citation: Breast Cancer Research 2024 26:149
  30. For patients with breast cancer undergoing neoadjuvant chemotherapy (NACT), most of the existing prediction models of pathologic complete response (pCR) using clinicopathological features were based on standar...

    Authors: Fangyuan Zhao, Eric Polley, Julian McClellan, Frederick Howard, Olufunmilayo I. Olopade and Dezheng Huo
    Citation: Breast Cancer Research 2024 26:148
  31. Obesity is an important risk factor for breast cancer in women before and after menopause. Adipocytes, key mediators in the tumor microenvironment, play a pivotal role in the relationship between obesity with ...

    Authors: Shengzi Jin, Yingce Zheng, Ding Li, Xingyao Liu, Tingting Zhu, Shuang Wang, Zhonghua Liu and Yun Liu
    Citation: Breast Cancer Research 2024 26:147
  32. Epigenetic dysregulation affecting oncogenic transcription and DNA damage response is a hallmark of cancer. The histone demethylase KDM4B, a factor regulating these processes, plays important roles in estrogen...

    Authors: Wenwen Wu, Jing Zhu, Naoe Taira Nihira, Yukiko Togashi, Atsushi Goda, Junki Koike, Kiyoshi Yamaguchi, Yoichi Furukawa, Takuya Tomita, Yasushi Saeki, Yoshikazu Johmura, Makoto Nakanishi, Yasuo Miyoshi and Tomohiko Ohta
    Citation: Breast Cancer Research 2024 26:146
  33. Breast cancer (BC) rates have been increasing in young women in the U.S. Alcohol is an established risk factor for breast cancer and has been consistently associated with hormone receptor positive cancers, the...

    Authors: Jianjiu Chen, Rebecca Kehm, Wan Yang and Mary Beth Terry
    Citation: Breast Cancer Research 2024 26:145
  34. This study used real-world observational data to compare profiles of patients receiving different first-line treatment for hormone receptor positive (ER+), HER2 negative, metastatic breast cancer (MBC): CDK4/6...

    Authors: Asal Pilehvari, Gretchen Kimmick, Wen You, Gloribel Bonilla and Roger Anderson
    Citation: Breast Cancer Research 2024 26:144
  35. Mortality from breast cancer is principally due to tumor recurrence. Recurrent breast cancers arise from the pool of residual tumor cells, termed minimal residual disease, that survive treatment and may exist ...

    Authors: Samantha Dwyer, Jason Ruth, Hans E. Seidel, Amelie A. Raz and Lewis A. Chodosh
    Citation: Breast Cancer Research 2024 26:143
  36. Breast cancer patients have an increased risk of cardiometabolic disease and for many patients, adjuvant therapy causes an altered lipid profile, insulin resistance and inflammation. Previous follow-up studies...

    Authors: Agnes Lindholm, Marie-Louise Abrahamsen, Kristian Buch-Larsen, Djordje Marina, Michael Andersson, Jørn Wulff Helge, Peter Schwarz, Flemming Dela and Linn Gillberg
    Citation: Breast Cancer Research 2024 26:142
  37. Breast cancer (BC) is the most common cancer in women and incidence rates are increasing; metabolomics may be a promising approach for identifying the drivers of the increasing trends that cannot be explained ...

    Authors: Hui-Chen Wu, Yunjia Lai, Yuyan Liao, Maya Deyssenroth, Gary W. Miller, Regina M. Santella and Mary Beth Terry
    Citation: Breast Cancer Research 2024 26:141
  38. Bidirectional crosstalk between HER2 and estrogen receptor (ER) pathways may influence outcomes and the efficacy of endocrine therapy (ET). Low HER2 expression levels (HER2-low) have emerged as a predictive bi...

    Authors: Guilherme Nader-Marta, Christian Singer, Dominik Hlauschek, Angela DeMichele, Paolo Tarantino, Evandro de Azambuja, Georg Pfeiler, Miguel Martin, Justin M. Balko, Zbigniew Nowecki, Marija Balic, Adam M. Brufsky, Arlene Chan, Patrick G. Morris, Tufia Haddad, Sibylle Loibl…
    Citation: Breast Cancer Research 2024 26:140
  39. Elevated mammographic density (MD) for a woman’s age and body mass index (BMI) is an established breast cancer risk factor. The relationship of parity, age at first birth, and breastfeeding with MD is less cle...

    Authors: Jessica O’Driscoll, Anya Burton, Gertraud Maskarinec, Beatriz Perez-Gomez, Celine Vachon, Hui Miao, Martín Lajous, Ruy López-Ridaura, A. Heather Eliassen, Ana Pereira, Maria Luisa Garmendia, Rulla M. Tamimi, Kimberly Bertrand, Ava Kwong, Giske Ursin, Eunjung Lee…
    Citation: Breast Cancer Research 2024 26:139
  40. Patients with pathologic complete response (pCR) to neoadjuvant chemotherapy for invasive breast cancer (BC) have better outcomes, potentially warranting less extensive surgical and systemic treatments. Early ...

    Authors: Bruno Valentin Sinn, Katharina Sychra, Michael Untch, Thomas Karn, Marion van Mackelenbergh, Jens Huober, Wolfgang Schmitt, Frederik Marmé, Christian Schem, Christine Solbach, Elmar Stickeler, Hans Tesch, Peter A. Fasching, Andreas Schneeweiss, Volkmar Müller, Johannes Holtschmidt…
    Citation: Breast Cancer Research 2024 26:138
  41. Breast cancer is the most common malignant tumor among women worldwide and remains one of the leading causes of death among women. Its incidence and mortality rates are continuously rising. In recent years, wi...

    Authors: Bitao Jiang, Lingling Bao, Songqin He, Xiao Chen, Zhihui Jin and Yingquan Ye
    Citation: Breast Cancer Research 2024 26:137
  42. Despite known benefits of physical activity in reducing breast cancer risk, its impact on mammographic characteristics remain unclear and understudied. This study aimed to investigate associations between pre-...

    Authors: Öykü Boraka, Hanna Sartor, Li Sturesdotter, Per Hall, Signe Borgquist, Sophia Zackrisson and Ann H. Rosendahl
    Citation: Breast Cancer Research 2024 26:136
  43. Breast cancer is common worldwide. Phosphoglycerate mutase 5 (PGAM5) belongs to the phosphoglycerate mutase family and plays an important role in many cancers. However, research on its role in breast cancer re...

    Authors: Nannan Zhang, Quhui Wang, Yunpeng Lu, Feiran Wang and Zhixian He
    Citation: Breast Cancer Research 2024 26:135
  44. The heterogeneous biology of ductal carcinoma in situ (DCIS), as well as the variable outcomes, in the setting of numerous treatment options have led to prognostic uncertainty. Consequently, making treatment d...

    Authors: Elissa M. Ozanne, Kellyn Maves, Angela C. Tramontano, Thomas Lynch, Alastair Thompson, Ann Partridge, Elizabeth Frank, Deborah Collyar, Desiree Basila, Donna Pinto, Terry Hyslop, Marc D. Ryser, Shoshana Rosenberg, E. Shelley Hwang and Rinaa S. Punglia
    Citation: Breast Cancer Research 2024 26:134
  45. Premenopausal, high-risk, hormone receptor-positive breast cancer patients are often treated with ovarian suppression in combination with aromatase inhibitors (AI). This combination has important adverse effec...

    Authors: Patrícia Taranto, Diogo de Brito Sales, Fernando Cotait Maluf, Rafael Aliosha Kaliks Guendelmann, Luciano de Melo Pompei, Alessandro Leal, Antonio Carlos Buzaid and Gustavo Schvartsman
    Citation: Breast Cancer Research 2024 26:133
  46. Despite evidence indicating the dominance of cell-of-origin signatures in molecular tumor patterns, translating these genome-wide patterns into actionable insights has been challenging. This study introduces b...

    Authors: Mohamed Omar, J. Chuck Harrell, Rulla Tamimi, Luigi Marchionni, Cihat Erdogan, Harikrishna Nakshatri and Tan A. Ince
    Citation: Breast Cancer Research 2024 26:132
  47. Breast cancer is the second leading cause of death in women, with invasive ductal carcinoma (IDC) and invasive lobular carcinoma (ILC) as the two most common forms of invasive breast cancer. While estrogen rec...

    Authors: Abraham T. Phung, Jaimin R. Shah, Tao Dong, Tony Reid, Christopher Larson, Ana B. Sanchez, Bryan Oronsky, William C. Trogler, Andrew C. Kummel, Omonigho Aisagbonhi and Sarah L. Blair
    Citation: Breast Cancer Research 2024 26:131
  48. Although tumor cells undergoing epithelial–mesenchymal transition (EMT) typically exhibit spindle morphology in experimental models, such histomorphological evidence of EMT has predominantly been observed in r...

    Authors: Huang-Chun Lien, Hui-Chieh Yu, Wen-Hsuan Yu, Su-Fang Lin, Tom Wei-Wu Chen, I-Chun Chen, Li-Ping Hsiao, Ling-Chun Yeh, Yu-Chia Li, Chiao Lo and Yen-Shen Lu
    Citation: Breast Cancer Research 2024 26:130

Annual Journal Metrics

  • Citation Impact 2023
    Journal Impact Factor: 6.1
    5-year Journal Impact Factor: 7.1
    Source Normalized Impact per Paper (SNIP): 1.865
    SCImago Journal Rank (SJR): 2.578

    Speed 2024
    Submission to first editorial decision (median days): 12
    Submission to acceptance (median days): 145

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    Downloads: 2,971,481
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