Table 3 Hazard ratios and 95% confidence intervals of candidate prognostic factors of the multivariable Cox proportional hazards models on overall survival of 417 breast cancer patients of the ISE cohort
10-year Follow-Up | 15-year Follow-Up | |||
|---|---|---|---|---|
Hazard Ratio (95% CI) | P | Hazard Ratio (95% CI) | P | |
Global Health Status/Quality of Life* (lowest tertile vs. intermediate and highest tertiles) | 1.60 (0.91 to 2.82) | 0.10 | 1.52 (0.97 to 2.37) | 0.07 |
Tumour Size | 2.94 (1.65 to 5.25) | < 0.005 | 1.98 (1.24 to 3.18) | < 0.005 |
Nodal Involvement | 2.64 (1.45 to 4.83) | < 0.005 | 1.93 (1.16 to 3.21) | 0.01 |
Grading | ||||
Grade 1 | Reference | |||
Grade 2 | 0.72 (0.33 to 1.57) | 0.41 | 0.80 (0.44 to 1.45) | 0.46 |
Grade 3 | 0.89 (0.35 to 2.24) | 0.81 | 0.86 (0.41 to 1.80) | 0.69 |
Hormone Receptor Positivity (ER/PR) | 0.52 (0.21 to 1.27) | 0.15 | 0.52 (0.26 to 1.05) | 0.07 |
Age | 1.04 (1.01 to 1.08) | 0.008 | 1.08 (1.05 to 1.11) | < 0.005 |
Body Mass Index (kg/m2) | 1.06 (0.99 to 1.13) | 0.07 | 1.02 (0.97 to 1.08) | 0.39 |