Biomechanical parameters quantified by MR elastography for predicting response to neoadjuvant chemotherapy and disease-free survival in breast cancer: a prospective longitudinal study

Table 3 Diagnostic performances of models concerning prediction of pathologic complete response to neoadjuvant chemotherapy

Model	AUC^†	Sensitivity	Specificity	Accuracy	PPV	NPV
Clinicopathologic model^§	0.79 (0.73, 0.84)	66 (41/62)	80 (138/173)	76 (179/235)	54 (41/76)	87 (138/159)
MRI model^*	0.92 (0.87, 0.95)	90 (56/62)	82 (142/173)	84 (198/235)	64 (56/87)	96 (142/148)
Combined model^ǁ	0.95 (0.92, 0.98)	89 (55/62)	90 (156/173)	90 (211/235)	76 (55/72)	96 (156/163)

Note.—Unless otherwise specified, data are presented as percentages (numbers of participants).
AUC = area under the receiver operating characteristic curve; PPV = positive predictive value; NPV = negative predictive value
^†Data are presented as mean AUCs (bootstrapped 95% confidence intervals)
^§Including progesterone receptor and human epidermal growth factor receptor-2
^*Including T2-c and T2-φ
^ǁIncluding progesterone receptor, human epidermal growth factor receptor-2, T2-c, and T2-φ

ISSN: 1465-542X