Table 2 Clinical and molecular characteristics of relapsed patients, including ctDNA detection dynamics
Patient | Type of recurrence (metastatic/local) | Metastatic site | Time from diagnosis to relapse (months) | Lead time to clinical relapse (months) | ctDNA detected in first blood draw (Yes/No) | ctDNA detected in all blood draws | ctDNA detected in any blood draw |
|---|---|---|---|---|---|---|---|
2 | Local + Metastatic | Bone (multiple) | 130 | 64 | Yes | No | Yes |
7 | Local | Breast | 158 | 68 | Yes | No | No |
13 | Metastatic | Bone | 178 | – | – | – | – |
14 | Metastatic | Liver (multiple) | 164 | – | – | – | – |
18 | Metastatic | Brain | 83 | 17 | Yes | No | No |
19 | Local | Breast (Axillary lymph node) | 187 | – | – | – | – |