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Fig. 4 | Breast Cancer Research

Fig. 4

From: A ROR1 targeted bispecific T cell engager shows high potency in the pre-clinical model of triple negative breast cancer

Fig. 4

ROR1/CD3 TCE killed ROR1-expressing TNBC cells. (A) The cytotoxic lysis of ROR1/CD3 antibody to TNBC cells were detected by measuring the lactate dehydrogenase release. (B-G) Human PBMCs were incubated with ROR1/CD3 antibody molecule and the cytokine release in the supernatants was detected by ELISA. Both the cytotoxic and cytokine release experiments were performed with three tecnological replicates, and validated by another PBMC donor

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Breast Cancer Research

ISSN: 1465-542X

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