Table 2 Lead time between first ctDNA detection and clinical disease recurrence

Molinero 2022 [28]

6.1

0-30.5

After adjuvant

Gupta 2023 [25]

3.85

0.6–11

After adjuvant

Stecklein 2023 [35]

4.7

Not reported

After all treatment

Turner 2023 [36] (observation arm)*

4.1

Not reported

After all treatment*

Turner 2023 [36)] (intervention arm)*

1.6

Not reported

After all treatment*

Shaw 2024 [34]

8

0–19

After all treatment

Chen 2017 [23]

4.2

0.07–8.87

During adjuvant

Chen 2020 [24]

Not reported

0.07–20.93

First day of adjuvant