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Fig. 8 | Breast Cancer Research

Fig. 8

From: Unveiling the key mechanisms of FOLR2+ macrophage-mediated antitumor immunity in breast cancer using integrated single-cell RNA sequencing and bulk RNA sequencing

Fig. 8

The influence of CXCR3 deletion on the antitumor immunity of FOLR2+ macrophages. Note A Morphological images of tumor tissues from each group of mice and statistical analysis of tumor tissue volumes; B Immunohistochemical staining images (Ki67) of tumor tissues from each group of mice (scale bar: 25 µm) and statistical analysis of the proportion of positive cells; C Flow cytometry analysis showing the percentage of IFN-γ-positive cells in CD8+ T cells in tumors of each group of mice, along with bar graphs for statistical comparison; D Flow cytometry analysis showing the percentage of IFN-γ-positive cells in CD8+ T cells in the spleens of each group of mice, along with bar graphs for statistical comparison; E ELISA measurement of serum IFN-γ concentrations in each group of mice; *indicates P < 0.05, **indicates P < 0.01, ***indicates P < 0.001; there were 10 animals in each experimental group

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Breast Cancer Research

ISSN: 1465-542X

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