Table 3 Results of mixed effects model analysis of trajectory differences by responder status for biomarkers. Bold font p-values indicate statistical significance (p-value < 0.05). (SE: standard error)
Biomarker | Estimate | SE | P-value |
|---|---|---|---|
\(\:\varvec{V}\varvec{D}\) | -0.0007 | 0.0003 | 0.023 |
\(\:\varvec{N}\varvec{V}\) | -0.069 | 0.038 | 0.071 |
\(\:\varvec{N}\varvec{B}\) | -0.043 | 0.029 | 0.135 |
\(\:{\varvec{\tau\:}}_{\varvec{m}\varvec{e}\varvec{a}\varvec{n}}\) | -0.006 | 0.004 | 0.149 |
\(\:{\varvec{\tau\:}}_{\varvec{m}\varvec{a}\varvec{x}}\) | -0.009 | 0.004 | 0.049 |
\(\:{\varvec{D}}_{\varvec{m}\varvec{e}\varvec{a}\varvec{n}}\) | -3.899 | 2.251 | 0.086 |
\(\:{\varvec{D}}_{\varvec{m}\varvec{a}\varvec{x}}\) | -12.155 | 3.867 | 0.002 |
\(\:\varvec{F}\varvec{D}\) | -0.011 | 0.004 | 0.002 |
\(\:{\varvec{M}\varvec{D}}_{\varvec{m}\varvec{e}\varvec{a}\varvec{n}}\) | -0.005 | 0.002 | 0.034 |
\(\:{\varvec{M}\varvec{D}}_{\varvec{m}\varvec{a}\varvec{x}}\) | -0.013 | 0.005 | 0.022 |
\(\:{\varvec{B}\varvec{A}}_{\varvec{m}\varvec{e}\varvec{a}\varvec{n}}\) | -0.124 | 0.316 | 0.695 |
\(\:{\varvec{B}\varvec{A}}_{\varvec{m}\varvec{a}\varvec{x}}\) | -0.850 | 0.528 | 0.111 |