Fig. 2

qHDMI images, quantitative biomarkers and trend plots in a 36-year-old patient with breast cancer in the responder group. (a, b,c) Research B-mode US and (d, e,f) qHDMI images for their visits: (a, d) pre-chemotherapy, (b, e) mid-chemotherapy and (c, f) post-chemotherapy visits. Dashed blue and green curves are the segmented lesion boundaries before and after 2 mm dilation, respectively. Table under the images contains a selected set of qHDMI biomarkers calculated from the microvascular structure derived from the qHDMI images. The pre-mid-post plots represent trajectories of three of the biomarkers (\(\:NV\), \(\:{\tau\:}_{max}\), \(\:{MD}_{max})\) over time for this patient in the responder group