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Table 1 Demographic, pathologic, and therapy data, n = 213 patients. Parameters include all patients and are also sub-divided by HER2 status

From: Fluoroestradiol (FES) and Fluorodeoxyglucose (FDG) PET imaging in patients with ER+, HER2-positive or HER2-negative metastatic breast cancer

Patient/lesion characteristics

All patients, n = 213

Total

HER2-positive

HER2-negatve

Age at FES, years (range)

55 (23–79)

52 (28–74)

55 (23–79)

Race

Ā Ā Ā 

Caucasian

181 (85%)

Ā Ā 

Asian

9 (4%)

Ā Ā 

Black or African American

5 (2%)

Ā Ā 

American Indian or Alaska Native

4 (2%)

Ā Ā 

Unknown or Other

14 (7%)

Ā Ā 

HER2 status (n, % of total)

Ā 

33 (15%)

180 (85%)

Menopausal status

Ā Ā Ā 

Postmenopausal

158 (74%)

20 (61%)

138 (77%)

Premenopausal

50 (23%)

11 (33%)

39 (22%)

Male patients

5 (2%)

2 (6%)

3 (2%)

Histology

Ā Ā Ā 

Ductal

158 (74%)

28 (85%)

130 (72%)

Lobular

35 (16%)

4 (12%)

31 (17%)

Unknown

11 (5%)

1 (3%)

10 (5%)

Other

5 (2%)

0 (0%)

5 (3%)

Mixed

4 (2%)

0 (0%)

4 (2%)

Prior chemotherapy (n,%)

140 (66%)

26 (79%)

114 (63%)

Prior endocrine therapy (n,%)

109 (51%)

18 (55%)

91 (51%)

Therapy at time of FES (n,%)

Ā Ā Ā 

None

119 (56%)

16 (48%)

103 (57%)

Endocrine

80 (38%)

15 (45%)

65 (36%)

Chemotherapy

12 (6%)

2 (6%)

10 (5%)

Unknown

2 (1%)

0 (0%)

2 (1%)

Herceptin (HER2-positive only)

Ā 

11 (33%)

Ā 

Chemotherapy after FES (n,%)

45 (21%)

10 (30%)

35 (19%)

Endocrine therapy after FES

142 (67%)

19 (57%)

123 (68%)

Unknown therapy after FES

13 (6%)

2 (6%)

11 (6%)

FES scan machine

Ā Ā Ā 

Advance

191

31

160

DSTE

22

2

20

FDG scan machine

Ā Ā Ā 

Advance

175

30

145

DSTE

35

1

34

FDG and FES done on same machine

185

29

156