Fig. 4

Kaplan-Meier outcome analysis examining the association between HER2 status and time-to-progression (TTP) (A) and overall survival (OS) (B). The red line is patients with HER2- disease, while the blue line is patients with HER2 + disease. TTP had 157 patients in the analysis with 131 with HER2-negative disease and 26 with HER2-positive disease. OS analysis had 190 patients with 162 having HER2-negative disease and 28 with HER2-positive disease. Log-rank tests showed that for HER2 status the relationship was not significant for TTP (p = 0.323) or for overall survival (p = 0.087)