Fig. 1

SMYD4 was downregulated in breast cancer. (A)The SMYD4 expression level in multiple cancer types. (B)The SMYD4 expression level in breast cancer tissues compared with normal tissues. The survival analysis of breast cancer patients with high or lowSMYD4 expression levels, including cumulative DMFS (C), OS (D), and RFS (E), predicted by the KM plotter. The SMYD4 expression level in breast cancer cell lines detected by RTqPCR (F) and western blot (G). All experiments were repeat three times (n = 3), compared variances using F test and analyzed using an unpaired t-test, error bars represent SD.*p < 0.05; **p < 0.01;***p < 0.001