Fig. 2
From: Evolutionary measures show that recurrence of DCIS is distinct from progression to breast cancer
Cross-sectional SNV burden and divergence. Distribution of the number of SNVs per patient in the two cross-sectional cohorts A and the two lesion types (DCIS vs. IDC) present in the synchronous cohort B. Distribution of SNV genetic divergence (percentage of private mutations) per patient in the two cross-sectional cohorts C. We calculated divergence for tumors with at least five mutations in the union of the two samples, which explains the lower number of tumors per group. P-values shown if p ≤ 0.1, A, C Mann–Whitney U, B Paired-samples sign test. Interquartile range (vertical line) and median (point) in burgundy, N: number of patients