Fig. 1
From: Natural killer cells occupy unique spatial neighborhoods in HER2- and HER2+ human breast cancers
Overview of identified cell types and human breast cancer specimens. (A) Cell types and corresponding markers that were used to identify the cell types. (B) Breast cancer cohorts evaluated in this study. HER2 status was assessed by IHC (cohort 1) or FISH (cohort 2). (C) Example images of H&E sections, CD45, and PanCK staining with the selected ROIs represented by the green boxes. Depending on tissue size, 1–6 ROI per specimen were analyzed in cohort 1, and 1–11 ROI per specimen were analyzed in cohort 2. In all images, scale bar = 1.0 mm. H&E = hematoxylin and eosin, ROI = region of interest