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Fig. 3 | Breast Cancer Research

Fig. 3

From: Genomic alterations are associated with response to aromatase inhibitor therapy for ER-positive postmenopausal ductal carcinoma in situ: (CALGB 40903, Alliance)

Fig. 3

Top genes from candidate gene and genome-wide analyses, ranked by p value for differential expression after letrozole treatment. Gene lists and pathways with p values are reported in Supplementary Tables S2, S3, and S4. PGR was both a candidate gene and a top-ranking gene in the genome-wide analysis. Genes indicated with an asterisk have been found to be sensitive to the timing of tissue fixation (Gao, et al., 2018), which differed in pre- and post-treatment samples

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