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Fig. 2 | Breast Cancer Research

Fig. 2

From: Genomic alterations are associated with response to aromatase inhibitor therapy for ER-positive postmenopausal ductal carcinoma in situ: (CALGB 40903, Alliance)

Fig. 2

A Proliferation rates (KI67) of the matched pre- and post-letrozole-treated DCIS specimens, color-coded by PAM50 subtypes. The five cases with a pathologic complete response (pCR) are shown in the pre-treatment column (triangles). There were 24 cases with matched pre- and post-treatment samples (circles). Cases that exhibited a subtype switch upon treatment are indicated by the change in color of the post-treatment dots. B Sankey diagram of PAM50 classifications of the 24 matched pre- and post-letrozole-treated DCIS specimens

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