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Fig. 1 | Breast Cancer Research

Fig. 1

From: Exploring the role of ESR1 mutations in metastatic hormone receptor-positive breast cancer T cell immune surveillance disruption

Fig. 1

Specific T cell responses induced byESR1 -derived peptides in healthy donors and metastatic breast patients. (A) Peripheral blood mononuclear cells (PBMC) from healthy donors and breast cancer patients were stimulated using ESR1 derived peptides, and an IFN-γ ELISpot assay was performed. (B) Frequency of positive responses induced by ESR1-derived peptides in healthy donors and metastatic breast cancer patients. (C) Distribution of women healthy donors (n = 12) vs. patients (n = 21) according to their T cell responses against 0, 1, and 2 or more ESR1 derived peptides

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Breast Cancer Research

ISSN: 1465-542X

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