Fig. 5

The lymphocyte density relative to the distance from the vessel (A) or tumour (B), and the vessel density (C) and size (D) relative to the distance from the tumour for the 38 ER-positive patients. The box plots display outliers as black circles beyond 1.5 times the interquartile range. Each randomly coloured dot represents an individual patient’s data for a specific distance range, and the same colour is used for each patient across all distance ranges, with lines connecting the dots to show the trend for that patient across the full range of distances. * \(p<0.05\) between consecutive regions assessed using two-tailed, paired t-tests