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Table 2 Adjusted sub-distribution hazard ratios for developing depression in breast cancer survivors compared to noncancer control group by age categories

From: Depression risk among breast cancer survivors: a nationwide cohort study in South Korea

Age group

 

Subjects, No.

Case, No.

Duration, PY

Incidence rate

(per 1,000 PY)

sHR (95% CI)

Model 1

Model 2

Model 3

All ages

Control

99,834

18,696

655078.6

28.5

1 (ref.)

1 (ref.)

1 (ref.)

 

Breast cancer

59,340

14,492

357111.2

40.6

1.39 (1.36–1.42)

1.39 (1.36–1.42)

1.39 (1.36–1.42)

Age ≤ 50

Control

49,312

7,039

333091.1

21.1

1 (ref.)

1 (ref.)

1 (ref.)

 

Breast cancer

29,922

6,516

183835.9

35.4

1.64 (1.58–1.69)

1.69 (1.58–1.69)

1.64 (1.58–1.70)

Age > 50

Control

50,522

11,657

321987.4

36.2

1 (ref.)

1 (ref.)

1 (ref.)

 

Breast cancer

29,418

7,976

173275.3

46

1.24 (1.20–1.27)

1.24 (1.21–1.28)

1.23 (1.20–1.27)

P for interaction

    

< 0.001

< 0.001

< 0.001

  1. Abbreviations: PY, person-years; sHR, sub-distribution hazard ratio; CI, confidence interval
  2. Model 1 : Unadjusted
  3. Model 2 : Age, income, residual location
  4. Model 3 : Age, income, residual location, diabetes mellitus, hypertension, dyslipidemia, chronic kidney disease, smoking status, alcohol drinking, physical activity, body mass index