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Table 1 List of top 20 genes with a significant fold change in high-TIL group compared to low-TIL group

From: Characterization of tumor-infiltrating lymphocytes and their spatial distribution in triple-negative breast cancer

Gene

Log2 fold change

p value

Adjusted p value

GNLY-mRNA

1.78

1.60E-06

0.0063

KLRC2-mRNA

2.22

9.93E-06

0.0170

CD83-mRNA

0.80

1.29E-05

0.0170

TGFB2-mRNA

-1.46

2.25E-05

0.0222

CCL5-mRNA

1.42

3.69E-05

0.0291

CCR6-mRNA

1.38

5.02E-05

0.0318

SELL-mRNA

1.36

5.64E-05

0.0318

IL2RB-mRNA

1.47

6.89E-05

0.0338

ISG20-mRNA

0.99

7.72E-05

0.0338

GZMB-mRNA

1.82

9.45E-05

0.0372

TAP1-mRNA

1.32

0.000183

0.0608

PRF1-mRNA

1.39

0.000185

0.0608

MICB-mRNA

1.03

0.000204

0.0619

CCR7-mRNA

1.61

0.000242

0.0668

PSMB9-mRNA

1.19

0.000254

0.0668

SOCS1-mRNA

1.15

0.000305

0.0704

KLRK1-mRNA

1.33

0.000308

0.0704

NOD2-mRNA

0.90

0.000343

0.0704

CD247-mRNA

1.23

0.000355

0.0704

GZMM-mRNA

1.27

0.000387

0.0704

  1. Log2 fold changes were calculated using tumors with low levels of TIL infiltration as the baseline
  2. p values were adjusted by Benzamini-Yekutieli procedure
  3. TIL, tumor-infiltrating lymphocyte