Fig. 3

The forest plot for associations between pairs of PCOS and BC in bidirectional MR analysis. The estimates presented in the forest plot were obtained using the LHC-MR method. A positive association is indicated by the odd ratio (OR > 1), while a negative association is indicated by OR < 1. The results of forward causality from LHC-MR method are in the up panel, and the results of reverse causality from the LHC-MR method are in the down panel