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Fig. 6 | Breast Cancer Research

Fig. 6

From: Ribosomal S6 kinase (RSK) plays a critical role in DNA damage response via the phosphorylation of histone lysine demethylase KDM4B

Fig. 6

Sensitivity of cells with different KDM4B status to IR. The indicated cells were irradiated at different doses (0, 1.25, 2.5, 5, and 10 Gy) and analyzed for clonogenic survival after 2 (for HeLa and HCT116) or 3 (for others) weeks. (A) WT vs. KDM4B-KO. (B) KDM4B-S666D vs. S666A. (C and D) WT cells with vs. without BI-D1870. Relative survivals from triplicate experiments are shown as averages ± SD. Statistical significances were calculated using the two-way ANOVA.

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Breast Cancer Research

ISSN: 1465-542X

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