Fig. 5
From: The deubiquitinating enzyme USP11 regulates breast cancer progression by stabilizing PGAM5
USP11 regulates ferroptosis in breast cancer through PGAM5 After transfecting NC, sh-USP11 and ov-PGAM5 into MCF-7 and MDA-MB-231 cells, Erastin (10 µ g/ml) or RSL3 (10ng/ml) were introduced into the culture medium on the third day.We measured the levels of ferrous ions (A), MDA content (B). (C) Subcutaneous tumor formation experiment in nude mice