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Fig. 2 | Breast Cancer Research

Fig. 2

From: Elevated expression of Aurora-A/AURKA in breast cancer associates with younger age and aggressive features

Fig. 2

Aurora kinase A (AURKA) expression associates with aggressive subtypes and young age. A Aurora kinase A (Aurora-A) expression across molecular subtypes (by IHC; in house cohort, n = 292), B molecular subtypes by PAM50 (in-house cohort, n = 116). C AURKA mRNA expression across molecular subtypes (by PAM50; METABRIC < 50 cohort, n = 204), D and age groups in METABRIC discovery cohort (n = 939), E METABRIC validation cohort (n = 845), F and METABRIC discovery cohort with luminal A cases only (n = 466). Data shown with error-bars representing 95% confidence interval of the mean, and P-values by Mann-Witney U-test

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