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Fig. 2 | Breast Cancer Research

Fig. 2

From: Autophagy is required for mammary tumor recurrence by promoting dormant tumor cell survival following therapy

Fig. 2

HER2 down-regulation induces autophagy in primary and dormant tumor cells in vivo. (A) HER2 and p62 levels evaluated by western blotting in orthotopic MTB/TAN primary tumors in the presence of doxycycline or following doxycycline withdrawal for 2 d. β-tubulin is shown as a loading control. (B) Representative images of subcellular localization of EGFP-LC3 in MTB/TAN primary orthotopic tumors or orthotopic tumors subjected to 2 d or 28 d of doxycycline withdrawal. Original magnification, x400

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Breast Cancer Research

ISSN: 1465-542X

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