Fig. 1

Strength, Weakness, Opportunity and Threat (SWOT) analysis for systematic immunohistochemistry in DCIS. Routine assessment of hormone receptor status and HER2 protein expression by systematic immunohistochemical analysis in DCIS could increase interobserver concordance of DCIS grading. HER2 status may be used to personalize treatment, with de-escalation of therapy in HER2-negative DCIS patients