Effect of testosterone therapy on breast tissue composition and mammographic breast density in trans masculine individuals

Table 2 The association of testosterone therapy (per six months duration) and the percentages (%) of each breast tissue region

	n	Exp(β)	95% CI	p value
% epithelium
Model 1	411	0.97	0.95–0.98	< 0.001
Model 2	207	0.96	0.94–0.98	0.001
Model 3	193	0.97	0.95–0.99	0.005
% fibrous stroma
Model 1	411	0.99	0.98–0.99	< 0.001
Model 2	207	0.99	0.98–1.00	0.02
Model 3	193	0.99	0.98–1.00	0.05
% fat
Model 1	411	1.02	1.00–1.04	0.01
Model 2	207	1.02	0.99–1.06	0.15
Model 3	193	1.01	0.98–1.05	0.39

Model 1 adjusted for age and year of surgery. Model 2 adjusted for age and year of surgery, race/ethnicity, BMI, chest binding, and oophorectomy status. Model 3 adjusted for age and year of surgery, race/ethnicity, BMI, chest binding, oophorectomy status, and estimated weekly testosterone dose. Confidence interval, CI

ISSN: 1465-542X