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Fig. 7 | Breast Cancer Research

Fig. 7

From: GNA13 suppresses proliferation of ER+ breast cancer cells via ERα dependent upregulation of the MYC oncogene

Fig. 7

Schematic diagram showing the findings from this study: in the ER+ subtype, loss of GNA13 results in increased proliferation and tumor formation suggesting a tumor suppressive role for GNA13 in this subtype. This phenotype is dependent on upregulation of MYC signaling pathway observed upon GNA13 silencing exclusively in ER+ cell lines, where loss of GNA13 drives the expression of MYC through increasing ERα driven estrogen signalling

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Breast Cancer Research

ISSN: 1465-542X

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