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Fig. 3 | Breast Cancer Research

Fig. 3

From: Circular RNA HSDL2 promotes breast cancer progression via miR-7978 ZNF704 axis and regulating hippo signaling pathway

Fig. 3

CircHSDL2 as a sponge for miR-7978 in BCa cells. (A) 11 predicted potential target miRNAs from three databases: RNAhybrid, miRanda, and CSCD. (B-C) 11 predicted miRNAs and their predicted binding sites with circHSDL2. (D) Relative Rluc activity of these candidate miRNA mimics co-transfected with wild-type circHSDL2 vectors. (E) Relative Rluc activity of miR-7978 mimics co-transfected with circHSDL2-wt or circHSDL2-mut vectors. (F) Schematic representations of circHSDL2-wt and circHSDL2-mut luciferase reporter vectors, along with the binding site of miR-7978 on circHSDL2 predicted by miRanda

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