Fig. 6

Changes in gene expression reflect gene set and developmental changes with elevated Spy1 expression. (a) Volcano plot depicting differentially expressed genes in Spy1 p53 null as compared to p53 null tumours. Normalized gene expression counts of (b) Chil1 (Chi3l1), (c) Prom1, (d) FoxA1 and (e) Cdkn1a from RNA sequencing data with BH-adjusted p-value from DESeq2 indicated in the top right of each graph