Fig. 5

Silencing TFAP2A inhibits proliferation of TNBC cells. Expression of TFAP2A was knocked down by siRNAs in MDA-MB-231 and BT-549 cells, cell proliferation was assessed by A MTS assay, B Colony formation assay, and C EdU assay. D Western blot analysis showing the expression levels of Ki67, TFAP2A, and the phosphorylation levels of ERK and AKT in MDA-MB-231 cells and E BT-549 cells with or without TFAP2A knockdown