Table 1 Univariate and multivariate logistic regression model for pCR according to clinicopathological and treatment factors

Age < 50y vs. ≧50y

1.307

0.798–2.141

0.287

cT1-2 vs. cT3

0.759

0.368–1.566

0.456

cN0 vs. cN1-3

0.726

0.410–1.285

0.272

Grade I-II vs. III

1.418

0.871–2.310

0.160

HR positive vs. negative

3.767

2.256–6.290

< 0.001

1.907

1.014–3.584

0.045

HER2 RNAscope score 1–4 vs. 5

10.545

5.893–18.872

< 0.001

10.865

5.547–21.281

< 0.001

TIL < 20% vs. ≧20%

2.082

1.226–3.534

0.007

2.057

1.068–3.961

0.031

NCTT subgroup

EC(F) to TH(P) vs. TH(P)

2.307

1.049–5.072

0.038

2.680

0.941–7.634

0.065

EC(F) to TH(P) vs. TH(P) to EC(F)

1.004

0.518–1.948

0.990

1.363

0.599–3.099

0.460

EC(F) to TH(P) vs. TCarboH(P)

1.405

0.700-2.819

0.339

1.096

0.435–2.764

0.846

Anti-HER2 blockade (mono vs. dual)

1.444

0.885–2.359

0.142

2.178

1.141–4.159

0.018