Table 4 Association between inflammation at baseline and cognitive domains impaired at year 2
Inflammatory markers at baseline | Episodic memory (n = 200) | Working memory (n = 197) | Processing speed (n = 197) | Attention (n = 194) | Executive function (n = 196) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |
IL-6 | 5.50 (1.43 to 36.60) | 0.03 | 0.98 (0.37 to 2.79) | 0.97 | 1.47(0.68 to 3.30) | 0.33 | 0.79 (0.24 to 2.58) | 0.69 | 0.75 (0.34 to 1.73) | 0.49 |
IL-8 | 0.94 (0.75 to 1.06) | 0.51 | 0.93 (0.76 to 1.05) | 0.42 | 0.96(0.85 to 1.04) | 0.40 | 0.91 (0.79 to 1.03) | 0.17 | 0.85 (0.69 to 0.98) | 0.07 |
CRP > 3 | 2.59 (0.91 to 7.04) | 0.07 | 1.23 (0.41 to 3.36) | 0.70 | 2.47(1.05 to 5.87) | 0.04 | 1.01 (0.24 to 4.04) | 0.99 | 2.04 (0.81 to 4.92) | 0.12 |
TNFα | 1.25 (0.95 to 1.63) | 0.09 | 0.64 (0.44 to 0.89) | 0.01 | 1.03(0.83 to 1.26) | 0.82 | 0.8 (0.53 to 1.16) | 0.26 | 0.93 (0.72 to 1.19) | 0.59 |