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Fig. 6 | Breast Cancer Research

Fig. 6

From: EDI3 knockdown in ER-HER2+ breast cancer cells reduces tumor burden and improves survival in two mouse models of experimental metastasis

Fig. 6

MALDI-MSI reveals altered GPC and PCho levels in tumors with silenced EDI3 expression. Representative images of HER2 staining and MALDI mass spectrometry imaging of tumors dissected from pancreas of mice eight weeks after intraperitoneal injection of non-induced (-Dox) and doxycycline-induced (+ Dox) HCC1954-luc shEDI3 with corresponding quantification of glycerophosphocholine (GPC), phosphocholine (PCho) and choline levels within the defined tumor regions (black lines), with the GPC/PCho ratio also provided. Scale bars represent 1 mm and 200 µm (zoomed). Values represent mean ± SD for six tumors per condition (*p < 0.05)

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Breast Cancer Research

ISSN: 1465-542X

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