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Fig. 2 | Breast Cancer Research

Fig. 2

From: Unraveling malignant phenotype of peritumoral tissue: transcriptomic insights into early-stage breast cancer

Fig. 2

Identification of signaling pathways alterations in early-stage IDC samples. KEGG functional enrichment was performed using GSEA with identified DEGs in PT compared to TT (A) or NT (B), and TT compared to NT (C). Green and red bars show the negative and positive NES values of each KEGG pathway, respectively. Pathways with FDR value ≤ 0.05 are represented by dark bars. Functional enrichment analysis with clustered Biological Processes GO terms were performed using GSEA with DEGs identified in PT compared to TT or NT, and TT compared to NT (D). Green cells and red cells show the negative and positive NES values of each GO term, respectively. Representative GO terms are shown (FDR value ≤ 0.05)

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Breast Cancer Research

ISSN: 1465-542X

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