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Table 1 Patient descriptive characteristics

From: CD163+ macrophages in the triple-negative breast tumor microenvironment are associated with improved survival in the Women’s Circle of Health Study and the Women’s Circle of Health Follow-Up Study

Characteristic

Overall

Black

White

p-value

Total

611

507 (83.0)

104 (17.0)

 

Age at diagnosis, Mean (SD)

53.6 (11.0)

53.8 (11.1)

52.5 (10.6)

0.25

BMI (kg/m2), Median (IQR)

29.9 (26.2–34.7)

30.5 (26.8–35.6)

26.6 (22.8–30.9)

< 0.001

ER status

   

0.01

 ER+

419 (68.6)

337 (66.5)

82 (78.8)

 

 ER-

192 (31.4)

170 (33.5)

22 (21.2)

 

Subtype

   

0.04

 Luminal

359 (59.2)

293 (58.4)

66 (63.5)

 

 HER2+

104 (17.2)

81 (16.1)

23 (22.1)

 

 Triple negative

143 (23.6)

128 (25.5)

15 (14.4)

 

Stage

   

0.96

 I

260 (42.6)

217 (42.8)

43 (41.3)

 

 II

269 (44.0)

222 (43.8)

47 (45.2)

 

 III/IV

82 (13.4)

68 (13.4)

14 (13.5)

 

Grade

   

0.003

 1

82 (13.6)

63 (12.6)

19 (18.8)

 

 2

213 (35.4)

167 (33.3)

46 (45.5)

 

 3

307 (51.0)

271 (54.1)

36 (35.6)

 

Tumor size (cm), Median (IQR)

2.0 (1.3–2.8)

2.0 (1.3–3.0)

1.9 (1.2–2.5)

0.28

Node status

   

0.45

 Positive

242 (40.4)

197 (39.7)

45 (43.7)

 

 Negative

357 (59.6)

299 (60.3)

58 (56.3)

 

Surgery

   

0.71

 No

13 (2.2)

12 (2.4)

1 (1.0)

 

 Yes

591 (97.8)

489 (97.6)

102 (99.0)

 

Chemotherapy

   

0.35

 No

200 (33.1)

170 (33.9)

30 (29.1)

 

 Yes

404 (66.9)

331 (66.1)

73 (70.9)

 

Radiation

   

< 0.001

 No

212 (35.2)

158 (31.5)

54 (53.5)

 

 Yes

390 (64.8)

343 (68.5)

47 (46.5)

 

Hormone therapy

   

0.75

 No

226 (37.5)

186 (37.2)

40 (38.8)

 

 Yes

377 (62.5)

314 (62.8)

63 (61.2)

 

Vital status

    

 Alive

419 (76.7)

361 (77.5)

58 (72.5)

 

 Breast cancer-specific death

66 (12.1)

54 (11.6)

12 (15.0)

 

 Non-breast cancer-specific death

61 (11.2)

51 (10.9)

10 (12.5)

 

 Follow-up time (years), median (IQR)

9.7 (7.4–12.3)

9.3 (7.2–11.0)

15.1 (13.4–16.1)

 
  1. Normally distributed continuous variables presented as mean (SD) and non-normally distributed variables shown as median (IQR). Categorical variables are shown as N (%). Differences between self-identified race assessed using Welch Two Sample t-test for normally distributed continuous variables, Wilcoxon rank sum test for non-normally distributed continuous variables, and Pearson’s Chi-squared or Fisher’s exact test for categorical variables
  2. Missingness as follows: BMI (1), subtype (5), grade (9), tumor size (5), node status (12), surgery (7), chemotherapy (7), radiation (9), hormone therapy (8), vital status (65), follow-up time (65)
  3. BMI body mass index (calculated as weight in kilograms divided by height in meters squared), ER Estrogen receptor