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Table 1 Population characteristics, by receipt of chemotherapy

From: Trends in chemotherapy use for early-stage breast cancer from 2006 to 2019

   

Among those receiving chemotherapy

 

Overall

Participants who received chemotherapy

(n, %)

Received trastuzumab and/or pertuzumab

(n, %)

Did not receive trastuzumab and/or pertuzumab

(n, %)

TOTAL

33,670

13,089 (39%)

3,548 (27%)

9,541 (73%)

Characteristic

    

Age at diagnosis (years)

    

18–39

1,509 (4.5%)

1,194 (9.1%)

365 (10.3%)

829 (8.7%)

40–49

5,283 (15.7%)

3,230 (24.7%)

802 (22.6%)

2,428 (25.4%)

50–64

13,656 (40.6%)

6,064 (46.3%)

1,619 (45.6%)

4,445 (46.6%)

65–79

10,568 (31.4%)

2,516 (19.2%)

715 (20.2%)

1,801 (18.9%)

80+

2,654 (7.9%)

85 (0.6%)

47 (1.3%)

38 (0.4%)

Race

    

White

25,130 (74.6%)

9,313 (71.2%)

2,406 (67.8%)

6,907 (72.4%)

Black or African American

2,459 (7.3%)

1,106 (8.4%)

261 (7.4%)

845 (8.9%)

Asian

5,544 (16.5%)

2,430 (18.6%)

819 (23.1%)

1,611 (16.9%)

American Indian or Alaskan Native

136 (0.4%)

50 (0.4%)

11 (0.3%)

39 (0.4%)

Native Hawaiian or Other Pacific Islander

240 (0.7%)

120 (0.9%)

31 (0.9%)

89 (0.9%)

More than once race

55 (0.2%)

21 (0.2%)

9 (0.3%)

12 (0.1%)

Unknown/missing

106 (0.3%)

49 (0.4%)

11 (0.3%)

38 (0.4%)

Ethnicity

    

Not Hispanic

29,341 (87.1%)

11,059 (84.5%)

3,037 (85.6%)

8,022 (84.1%)

Hispanic

4,328 (12.9%)

2,030 (15.5%)

511 (14.4%)

1,519 (15.9%)

Year of diagnosis

    

2006–2010

11,056 (32.8%)

4,566 (34.9%)

974 (27.5%)

3,592 (37.6%)

2011–2015

12,482 (37.1%)

4,816 (36.8%)

1,329 (37.5%)

3,487 (36.5%)

2016–2019

10,132 (30.1%)

3,707 (28.3%)

1,245 (35.1%)

2,462 (25.8%)

AJCC Stagea

    

Stage I

20,199 (60.0%)

4,223 (32.3%)

1,445 (40.7%)

2,778 (29.1%)

Stage II

11,456 (34.0%)

7,170 (54.8%)

1,733 (48.8%)

5,437 (57.0%)

Stage IIIA

2,015 (6.0%)

1,696 (13.0%)

370 (10.4%)

1,326 (13.9%)

Tumor subtype

    

Triple negative

3,523 (10.5%)

2,555 (19.5%)

25 (0.7%)

2,530 (26.5%)

Hormone receptor +/HER2 -

24,994 (74.2%)

6,955 (53.1%)

123 (3.5%)

6,832 (71.6%)

Hormone receptor +/HER2 +

3,166 (9.4%)

2,424 (18.5%)

2,344 (66.1%)

80 (0.8%)

Hormone receptor -/HER2 +

1,388 (4.1%)

1,067 (8.2%)

1,039 (29.3%)

28 (0.3%)

Unknown/not tested

599 (1.8%)

88 (0.7%)

17 (0.5%)

71 (0.7%)

  1. Abbreviations
  2. aAJCC: American Joint Committee on Cancer
  3. bHER2: Human epidermal growth factor receptor 2
  4. Note Hormone receptor + defined as ER + and/or PR+