Fig. 3
From: Association between human blood metabolome and the risk of breast cancer

Potential on-target side effects associated with HDL-C and acetate. Odds ratios (ORs) with their 95% confidence intervals (CIs) represent the effect estimates on the risk of multiple non-breast cancer diseases of per 10% reduction in risk for breast cancer by targeting HDL-C and acetate, respectively. Associations above the horizontal black midline represent deleterious side effects. In contrast, associations below the horizontal black midline represent beneficial side effects